Chronic neurologic symptoms are common in patients with FOP, particularly neuropathic pain, and especially in females (15%). Patients also experience other sensory abnormalities.
FOP is a disabling disease that may lead to immobilization, and as mobility begins to devolve, patients may become more prone to respiratory infection or right-sided congestive heart failure.
Hearing loss, usually conductive, is seen in approximately 50% of FOP cases. This symptom may be due to middle-ear ossification, but in other patients hearing impairment is sensorineural, involving the inner ear, cochlea, or the auditory nerve.
Learn more about clinical presentation of FOP.
Medscape © 2021 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Dirk M. Elston. Fast Five Quiz: Fibrodysplasia Ossificans Progressiva - Medscape - Jan 14, 2021.