Fast Five Quiz: Fibrodysplasia Ossificans Progressiva

Dirk M. Elston, MD

Disclosures

January 14, 2021

Because there is no approved medication to treat FOP to date, management involves early diagnosis, avoidance of iatrogenic harm, and symptomatic treatment of painful flare-ups. According to current treatment guidelines, a 4-day course of high-dose corticosteroids started at the initiation of a flare-up may help reduce the intense inflammation and tissue edema early in the disease course.

Corticosteroids should only be used for symptomatic treatment of flare-ups that affect major joints, the jaw, or the submandibular area in early stages of the disorder. However, in general, these agents should not be used for the symptomatic treatment of flare-ups that involve the back, neck, or trunk, owing to the long duration and episodic nature of these flare-ups and the uncertainty of determining when exactly such episodes began.

Learn more about treatment of FOP.

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