Fast Five Quiz: Spinal Muscular Atrophy

Stephen L. Nelson, Jr, MD, PhD

Disclosures

January 14, 2021

Most patients with SMA are affected by type 1 disease, or Werdnig-Hoffman disease, which can be particularly lethal. The median survival in patients with SMA type 1 is 7 months.

There is an inverse correlation between mortality and/or morbidity of SMA and age of onset. Early-onset disease confers the highest death rates. In patients with type 2 disease, length of survival is variable but is most often associated with respiratory complications.

Learn more about the prognosis associated with SMA.

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