Fast Five Quiz: Type 2 Inflammation in Severe Asthma

Zab Mosenifar, MD


January 20, 2021

Asthma is a heterogeneous chronic disease characterized by narrowing of airways of the lungs and can lead to debilitating symptoms. Type 2 inflammation in asthma is noted by the release of inflammatory cytokines, including interleukin (IL)-4, IL-5, and IL-13. These cytokines can activate eosinophils, which are produced in bone marrow and can migrate to the lungs, causing asthma symptoms.

Several biomarkers have recently been identified to play a role in the mechanisms underlying type 2 airway inflammation, including fractional exhaled nitric oxide (FeNO), serum IgE, periostin, and blood and sputum eosinophils. These severe asthma type 2 cytokines are currently being studied as potential therapeutic drug targets.

How much do you know about type 2 inflammation in severe asthma? Test your knowledge with this quick quiz.


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