Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal stem cell disorders with an inherent tendency for leukemic transformation. MDS may involve one, two, or three myeloid hematopoiesis cell lineages — erythrocytic, granulocytic, megakaryocytic — depending on the subtype and stage of the disease.
Prognosis of MDS varies widely and is based on disease-specific factors such as bone marrow blast cells, chromosomal abnormalities, and hematopoietic insufficiency, as well as unique patient factors, including age, comorbidities, and transfusion requirement. About 30% of MDS cases progress to acute myeloid leukemia (AML).
How much do you know about high-risk MDS? Test your knowledge with this quick quiz.
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Cite this: Emmanuel C. Besa. Fast Five Quiz: High-Risk Myelodysplastic Syndrome - Medscape - Feb 03, 2021.