The most common early symptoms of WM are fatigue and weakness characteristic of anemia, present in 80% of patients with symptomatic WM. Normocytic anemia, leukopenia, and thrombocytopenia may also be observed.
About 10% of WM patients have cold agglutinin disease, an acquired hemolytic anemia. Similarly, Raynaud syndrome (associated with both cold agglutinin disease and cryoglobulinemia) can occur in WM.
While progressive reduction in kidney function may occur with WM, acute kidney failure is rare.
Learn more about presentation of WM.
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Cite this: Emmanuel C. Besa. Fast Five Quiz: Waldenström Macroglobulinemia Complications - Medscape - Feb 01, 2021.