Skin biopsy is the easiest way to make a pathologic diagnosis of BPDCN in the majority of patients. In almost 50% of cases, skin findings precede other symptoms by 2.5 months, which makes biopsy an imperative step in diagnosing this aggressive, rapidly progressing cancer.
Bone marrow biopsy, peripheral blood flow cytometry, and PET scan are the next steps and are essential to confirm diagnosis.
Learn more about the diagnosis of BPDCN.
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Cite this: Emmanuel C. Besa. Fast Five Quiz: Blastic Plasmacytoid Dendritic Cell Neoplasm Presentation and Diagnosis - Medscape - Feb 23, 2021.