Fast Five Quiz: Primary Hyperoxaluria Type 1

Bradley Schwartz, DO

Disclosures

February 25, 2021

Primary hyperoxaluria type 1 (PH1) is a rare inherited metabolic disorder that is caused by a deficiency of the peroxisomal enzyme alanine-glyoxylate aminotransferase. This deficiency results in an overproduction of oxalate by the liver, which leads to urolithiasis, nephrocalcinosis, and renal failure. In as many as 50% of patients, end-stage kidney disease (ESKD) occurs by the fourth decade of life. Presently, combined liver and renal transplant is the only curative option.

How familiar are you with PH1? Test your knowledge with this quick quiz.

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