Fast Five Quiz: Primary Hyperoxaluria Type 1

Bradley Schwartz, DO


March 04, 2022

Figure 1. Light micrograph of a section through adult bone tissue affected by oxalosis (primary hyperoxaluria), showing mature bone (green), newly formed immature bone/osteoid (orange), and bone marrow.

Like other forms of primary hyperoxaluria, PH1 is an exceedingly rare disease. Of the approximately 1 in 58,000 individuals worldwide who are affected by primary hyperoxaluria, approximately 80% have PH1.

Higher rates of PH1 have been reported in isolated populations. Moreover, increased prevalence has been reported in countries where consanguineous marriages are common.

Learn more about the epidemiology of PH1.


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