Fast Five Quiz: Primary Hyperoxaluria Type 1

Bradley Schwartz, DO

Disclosures

February 25, 2021

PH1 may appear at any age. Among patients whose disease appears when they are adults, more than 50% have ESKD at presentation.

Patients with early-stage PH1 often have recurrent kidney stones and nephrocalcinosis, which cause a progressive decline in kidney function. In up to 90% of patients, nephrolithiasis is present at diagnosis.

Most of the signs and symptoms of the three types of primary hyperoxaluria are similar; however, ESKD tends to occur earlier and is slightly more common in patients with PH1 than in patients with PH2.

Learn more details on the presentation of PH1.

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