According to Shekarriz and colleagues, CT without contrast remains the most accurate imaging modality to detect the presence of kidney stones and for evaluating patients who may have a urinary stone, such as those who present with acute flank pain. Intravenous pyelography is rarely done anymore.
Although CT has many advantages, stones composed of protease inhibitors are not easily distinguishable on CT scans; intravenous contrast may be used to clarify the diagnosis.
Unlike stones made up of protease inhibitors, uric acid stones appear clearly on CT scans.
Learn more about the workup for PH1.
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Cite this: Bradley Schwartz. Fast Five Quiz: Primary Hyperoxaluria Type 1 Screening and Diagnosis - Medscape - Dec 15, 2022.