Fast Five Quiz: Spinal Muscular Atrophy in Adults

Stephen L. Nelson, Jr, MD, PhD


February 01, 2021

The clinical characteristics of SMA vary considerably in adult patients. In a recent comprehensive systematic review, hip dislocation or subluxation was observed in approximately one third (33%) of adult patients with SMA type 2 or 3. Other reported physical symptoms included limitations in muscle strength, mobility and posture, and respiratory and bulbar function, with variable severity among patients with different SMA types.

Cerebral dysfunction is not associated with SMA in adults. In fact, patients with SMA often have above-average intelligence.

Learn more about the clinical manifestations of SMA.


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