Fast Five Quiz: Alzheimer's Disease Signs and Symptoms

Jasvinder P. Chawla, MD, MBA

Disclosures

February 22, 2022

The criteria for an AD diagnosis established by the National Institute of Neurological Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (now known as the Alzheimer's Association) in 2011 require a patient to have slowly progressive memory loss of insidious onset. Importantly, the patient must be fully conscious because the diagnosis cannot be made in the context of clouded consciousness or delirium.

It is also important to differentiate AD from other more abrupt diseases like vascular dementia. Both AD and frontotemporal dementia (of which primary progressive aphasia and frontal lobe dementia are major aspects) result in significant memory loss. However, unlike AD, frontotemporal dementia initially appears as gradually worsening aphasia over several years, and patients eventually exhibit progressive dementia.

Learn more about the clinical guidelines for diagnosis of AD.

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