Fast Five Quiz: Managing Progression of Relapsing-Remitting Multiple Sclerosis

Christopher Luzzio, MD; Kerstin Hellwig, MD


July 01, 2022

Steroids remain the cornerstone of treatment for acute relapses. Although methylprednisolone (Solu-Medrol) can hasten recovery from an acute exacerbation of MS, there is no clear evidence that it can influence overall disease progression.

For severe attacks, if steroids are contraindicated or ineffective, plasma exchange (plasmapheresis) can be used on a short-term basis.

Although anti-inflammatory treatment has been considered as an approach for acute transverse myelitis and acute disseminated encephalitis, few supporting data have been reported. Dexamethasone is commonly used. In the context of optic neuritis, anti-inflammatory treatment can shorten the period of visual dysfunction and decrease pain but has not been shown to improve visual outcomes.

Risk for MS relapse decreases with age.

Learn more about treatment of acute relapses.


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