Lactitol exerts an osmotic effect, causing an influx of water into the small intestine that results in a laxative effect in the colon. It is indicated for adults with chronic idiopathic constipation.
Approval was based on data from approximately 800 patients that included a 6-month placebo-controlled trial and a 3-month active-controlled trial with lubiprostone. (Pizensy prescribing information)
Other notable approvals
Suprep (sodium sulfate/potassium sulfate/magnesium sulfate) - Indication for colonoscopy bowel preparation expanded to include children aged 12 years and older
Sutab (sodium sulfate/magnesium sulfate/potassium chloride) - New oral tablet regimen for bowel preparation for colonoscopy
Medscape © 2021 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: FDA Approvals, Highlights, and Summaries: Gastroenterology - Medscape - Feb 24, 2021.