Fast Five Quiz: Caffeine Clinical Concerns

Mary L. Windle, PharmD


February 12, 2021

The relationship between caffeine intake and various health conditions is an ongoing and popular area of investigation.

A systematic review found that patients with chronic liver disease who consume coffee have a decreased risk for progression to cirrhosis, a lower mortality rate, and a lower rate of hepatocellular carcinoma development.

A large population-based study found that moderate, daily coffee consumption had no apparent adverse effect for triggering incident heart arrhythmias, and was even linked to a small but statistically significant decrease in arrhythmias.

The use of caffeine-containing medicines is associated with increased risk for hemorrhagic stroke, both subarachnoid hemorrhage and intracerebral hemorrhage.

An inverse relationship between consuming caffeine and all-cause mortality has been reported among patients with chronic kidney disease.

Read more about cirrhosis.


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