Fast Five Quiz: Parkinson's Disease Nonmotor Symptoms

Jasvinder P. Chawla, MD, MBA


February 25, 2021

Figure 2. Illustration of idiopathic rapid eye movement (REM) representing a saccade, the fast and simultaneous movement of both eyes in the same direction. REM sleep behavior disorder (RBD) manifests as unpleasant dreams and dream-enacting behaviors. RBD is recognized as a prodromal stage of Parkinson's disease.

Cognitive impairment in patients with Parkinson's disease can be subtle and may not be apparent until acute symptoms present. Although analogous progression of cognitive impairment and motor symptoms may occur, there is no correlation with the overall duration of disease.

Prevalence estimates of dementia in the Parkinson's disease population range from 20% to 40%, although nearly 80% of patients eventually develop cognitive decline. Patients with Parkinson's disease are six times more likely to develop dementia than those in the general population.

Visual hallucinations occur in 20%-40% of patients with Parkinson's disease. There is a strong correlation between the manifestation of psychosis and the need for nursing home placement or hospitalization, but early and effective treatment may decrease the need for placement and ease caregiver burden.

Learn more about the clinical manifestations of Parkinson's disease.


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