Anticholinergic agents may worsen TD and its impact. Improvement in TD severity ratings has been observed in up to 60% of patients after withdrawal from anticholinergics. However, caution should be exercised when deciding to reduce or taper anticholinergics in patients with acute drug-induced movements (eg, parkinsonism, dystonia) or tardive dystonia because these disorders could reemerge or worsen after withdrawal. In patients with TD and parkinsonism, amantadine may be a reasonable and beneficial alternative to anticholinergics.
Learn more about the management of TD.
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Cite this: Christoph U. Correll. Fast Five Quiz: Tardive Dyskinesia Management - Medscape - Jun 28, 2023.