TD is most common in patients with schizophrenia, schizoaffective disorder, or bipolar disorder who have been treated with antipsychotic medications for long periods. Occasionally, TD occurs in patients with other diagnoses as well. For example, TD can occur in people with fetal alcohol syndrome and other developmental disabilities.
TD is associated with long-term administration of antipsychotic medications, and these medications are less likely to be used to treat depression, or if antipsychotics are used, doses are generally low. Therefore, TD is not commonly associated with depression, although this is a possibility.
Parkinson's disease often presents with motor signs; however, these are different from the movements associated with TD. The initial finding of Parkinson's disease is an asymmetric resting tremor in the upper extremities. Over time, patients notice symptoms related to progressive bradykinesia, rigidity, postural instability, and gait difficulty.
Learn more about the etiology of TD.
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Cite this: Christoph U. Correll, James Robert Brasic. Fast Five Quiz: Tardive Dyskinesia Risk Factors - Medscape - Mar 17, 2023.