Fast Five Quiz: Progressive Fibrosing Interstitial Lung Disease Presentation and Diagnosis

Zab Mosenifar, MD


April 24, 2023

The most common findings on chest radiographs in patients with ILDs are widespread nodular and/or fine linear (reticular) shadowing and/or ground-glass opacities. As noted, HRCT usually confirms the diagnosis, and the fibrosis score can help determine prognosis.

Honeycombing is usually a late finding, which carries a poor prognosis.

The presence of nodules may be indicative of hypersensitivity pneumonitis, granulomatous disease, pulmonary Langerhans cell histiocytosis, and respiratory bronchiolitis interstitial lung disease.

A UIP pattern may be observed in patients with a progressive phenotype of fibrotic ILD and typically carries a worse prognosis.

Learn more about imaging studies of PF-ILD.


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