Fast Five Quiz: Rheumatoid Arthritis Interstitial Lung Disease Management

Zab Mosenifar, MD


April 05, 2021

There is growing evidence in support of the association between smoking, high rheumatoid factor titer, elevated anticitrullinated protein antibody levels, and RA-ILD.

The main objectives of comprehensive pulmonary rehabilitation include increased independence and improved quality of life, as well as fewer hospitalizations or shorter hospitalization time. Coupled with exercise, a pulmonary rehabilitation program may improve a patient's functional status. However, these activities generally do not slow disease progression. Pulmonary rehabilitation does not reverse airway obstruction or hyperinflation associated with chronic obstructive pulmonary disease, but it does allow for reversal of muscle deconditioning, ultimately enabling patients to walk farther and with less dyspnea.

International guidelines strongly recommend the long-term use of supplemental oxygen for patients with IPF and clinically significant resting hypoxemia (oxygen saturation [SaO2] less than or equal to 88% or partial pressure of oxygen [PaO2] < 55 mm Hg while breathing room air either at rest or upon exertion). Although there is no recommendation for patients with exertional hypoxemia, oxygen therapy may help these patients increase exercise capacity.

Learn more about guidelines for CTD-ILD.


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