In the context of schizophrenia, many of the features of depression and negative symptoms overlap, making it difficult to identify the source of the symptoms. In studies, it is challenging to assess whether a reduction in negative symptoms is a function of improvement in depression. For this reason, the Calgary Depression Scale for Schizophrenia assesses depressive symptoms and differentiate them from negative symptoms of schizophrenia. Depression in patients with schizophrenia is often the result of symptoms themselves, or the lower quality of life caused by their symptoms. Depressed patients are at a higher risk for suicide than patients who are not depressed.
Suicide attempts are lower in patients treated with clozapine than with other antipsychotic agents.
Learn more about complications of schizophrenia.
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Cite this: Stephen Soreff. Fast Five Quiz: Schizophrenia Comorbidities - Medscape - Apr 22, 2021.