Fast Five Quiz: Chronic Kidney Disease (CKD) Management

A. Brent Alper, Jr, MD, MPH; Patrick Rossignol, MD


February 03, 2023

Severe metabolic acidosis is an indication for renal replacement therapy in CKD, per Harrison. Other indications include:

  • Hyperkalemia

  • Pericarditis

  • Encephalopathy

  • Intractable volume overload

  • Failure to thrive and malnutrition

  • Peripheral neuropathy

  • Intractable gastrointestinal symptoms

Additionally, renal replacement therapy is indicated in asymptomatic patients with a GFR of 5-9 mL/min/1.73 m², regardless of the cause of CKD or the presence or absence of other comorbidities.

Learn more details about the management of CKD.


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