Severe metabolic acidosis is an indication for renal replacement therapy in CKD, per Harrison. Other indications include:
Intractable volume overload
Failure to thrive and malnutrition
Intractable gastrointestinal symptoms
Additionally, renal replacement therapy is indicated in asymptomatic patients with a GFR of 5-9 mL/min/1.73 m², regardless of the cause of CKD or the presence or absence of other comorbidities.
Learn more details about the management of CKD.
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Cite this: A. Brent Alper, Patrick Rossignol. Fast Five Quiz: Chronic Kidney Disease (CKD) Management - Medscape - Feb 03, 2023.