Dialysis is an important treatment in the management of CKD. However, most currently available dialysis techniques are unsuccessful in removing excess phosphate to the degree of normalizing phosphate concentration because the rate of phosphate transfer from the intracellular pool to the extracellular pool is relatively slow.
Even when combined with dietary phosphate restriction, dialysis treatments are usually unsuccessful in managing hyperphosphatemia. Most patients with CKD require phosphate binders to control their hyperphosphatemia.
In patients receiving peritoneal dialysis therapy, dialytic removal of phosphate is approximately 300 mg/day. In patients who receive hemodialysis three times per week, dialytic removal of phosphate corresponds to 800 mg/session or 350 mg/day.
Learn more details about managing the pathologic manifestations of CKD.
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Cite this: A. Brent Alper, Patrick Rossignol. Fast Five Quiz: Chronic Kidney Disease (CKD) Management - Medscape - Feb 03, 2023.