Fast Five Quiz: Myelodysplastic Syndrome Pathology

Emmanuel C. Besa, MD


May 12, 2021

Myelodysplastic syndrome (MDS) refers to a group of related hematopoietic disorders characterized by peripheral blood cytopenias, abnormal blood cell development, and clonal genetic markers. MDS comprises several distinct entities with particular clinical behavior and clinicopathologic features. The World Health Organization classification of MDS includes these disorders:

  • MDS with single-lineage dysplasia (MDS-SLD)

  • MDS with multilineage dysplasia (MDS-MLD)

  • MDS with ring sideroblasts (MDS-RS), which are further subclassified into MDS-RS with single-lineage dysplasia and MDS-RS with multilineage dysplasia

  • MDS with excess blasts (MDS-EB)

  • MDS with isolated del(5q)

  • MDS, unclassifiable (MDS-U)

How much do you know about the pathology of these heterogenous diseases? Test your knowledge with this quick quiz.


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