Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease worldwide. It is characterized by progressive development of renal cysts, hypertension, and destruction of the kidney parenchyma. Most patients with ADPKD develop end-stage renal disease by 60 years of age. Although ADPKD may present in utero and early in life, early-stage disease is often asymptomatic and undiagnosed as a result of compensatory glomerular hyperfiltration. In recent years, however, important advances in diagnosing, prognosticating, and understanding the pathogenesis and natural course of ADPKD have been made. Early nephrology referral and implementation of nephron-protective strategies may result in clinically important improvements.
How familiar are you with the presentation and diagnosis of ADPKD? Test your knowledge with this quick quiz.
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Cite this: Neera K. Dahl. Fast Five Quiz: Autosomal Dominant Polycystic Kidney Disease Presentation and Diagnosis - Medscape - Jun 29, 2021.