Myasthenia gravis (MG) is a rare autoimmune neuromuscular disorder in which antibodies form against postsynaptic nicotinic acetylcholine receptors (AChRs) located at the motor endplate of the neuromuscular junction (NMJ). With a worldwide prevalence of 12.4 people per 100,000 population, MG is one of the most common and well-understood neuromuscular diseases. Other antigenic targets of the NMJ, muscle-specific receptor tyrosine kinase (MuSK) antibody and low-density lipoprotein receptor-related protein 4 antibody, have also been implicated in 5%-8% of all patients with MG. The detection of AChR, via antibody test, in patients with typical clinical symptoms is a key diagnostic marker of MG and helps define the disease subtypes.
How much do you know about the signs and symptoms of MG? Test your knowledge with this quick quiz.
Medscape © 2023 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Richard Nowak, Nicholas J. Silvestri. Fast Five Quiz: Myasthenia Gravis Signs and Symptoms - Medscape - Sep 27, 2023.
Comments