Patients in whom definitive surgery may be delayed would be appropriate candidates for preoperative systemic therapy. Other candidates would be:
Patients with inoperable breast cancer:
Inflammatory breast cancer
Bulky or matted cN2 axillary nodes
cN3 nodal disease
cT4 tumors
In patients with operable breast cancer, preoperative systemic therapy is preferred for:
HER2-positive disease and triple-negative breast cancer, if cT ≥ 2 or cN ≥ 1
Large primary tumor relative to breast size in a patient who desires breast conservation
cN+ disease likely to become cN0 with preoperative systemic therapy
Learn more about the treatment of breast cancer.
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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Pavani Chalasani. Fast Five Quiz: Breast Cancer Treatment - Medscape - Jul 12, 2021.
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