Fast Five Quiz: Breast Cancer Treatment

Pavani Chalasani, MD, MPH

Disclosures

July 12, 2021

Patients in whom definitive surgery may be delayed would be appropriate candidates for preoperative systemic therapy. Other candidates would be:

Patients with inoperable breast cancer:

  • Inflammatory breast cancer

  • Bulky or matted cN2 axillary nodes

  • cN3 nodal disease

  • cT4 tumors

In patients with operable breast cancer, preoperative systemic therapy is preferred for:

  • HER2-positive disease and triple-negative breast cancer, if cT ≥ 2 or cN ≥ 1

  • Large primary tumor relative to breast size in a patient who desires breast conservation

  • cN+ disease likely to become cN0 with preoperative systemic therapy

Learn more about the treatment of breast cancer.

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