Fast Five Quiz: Statins

Mary L. Windle, PharmD


May 17, 2021

Adverse effects reportedly associated with atorvastatin include the following:

  • Diarrhea

  • Nasopharyngitis

  • Arthralgia

  • Insomnia

  • Urinary tract infection

  • Nausea

  • Dyspepsia

  • Increased aminotransferase levels

  • Muscle spasms

  • Musculoskeletal pain

  • Myalgia

  • Limb pain

  • Pharyngolaryngeal pain

A randomized trial examined the association of frequently intolerable statin side effects, such as muscle weakness and pain. The findings suggested that although many patients who report such symptoms while taking statins are indeed feeling them, they are potentially a nocebo effect. The SAMSON study found that 90% of the symptomatic burden was elicited by placebo tablets as well. Elsewhere, a study on erectile dysfunction found that statin use was associated with a small improvement in erectile function.

Read more dosing indications and clinical information about atorvastatin.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as: