Fast Five Quiz: Statins

Mary L. Windle, PharmD


May 17, 2021

Statins are contraindicated in patients with active hepatic disease, as well as those who have unexplained persistent elevations in aminotransferase levels. Pregnancy and breastfeeding are also considered contraindications.

Although some neurologic adverse effects have been reportedly associated with statin use, the medications may have therapeutic potential in patients with stroke, Alzheimer's disease, Parkinson's disease, multiple sclerosis, and primary brain tumors. Statins have been shown to potentially reduce the risk for mortality in patients with chronic obstructive pulmonary disease. Statins also appear to protect the kidneys through cholesterol reduction, as well as other mechanisms. Some studies have shown that statin therapy slows the decline of the glomerular filtration rate and reduces proteinuria in patients with chronic kidney disease.

Read more about contraindications and cautions for atorvastatin use.


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