Fast Five Quiz: Type 2 Diabetes Incretin-Based Therapy

Romesh Khardori, MD, PhD; Anne L. Peters, MD


April 28, 2023

The most common side effect that causes drug discontinuation in patients with type 2 diabetes taking GLP-1 RAs is gastrointestinal intolerance. One study noted an increased risk for gallstones or biliary tract-related events with the use of GLP-1 RAs.

GLP-1 RAs are available in oral and injectable formulations.

An increased risk for genital fungal infections and urinary tract infections has been observed with SGLT2 inhibitors; however, most are easily managed. Urinary tract infections have not been observed with the use of DPP-4 inhibitors.

Learn more about the side effects of type 2 diabetes treatments.


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