Figure 1. A baby with atopic dermatitis.
The risk factors that are consistently associated with the development of AD are loss of function mutations in the FLG gene and a family history of atopy. Although markers for prognosis in AD are inconsistent, FLG gene null mutations tend to predict a more severe and protracted disease course.
Although breastfeeding during the first 4 months of life may reduce the incidence and severity of childhood atopic disease, the reduction is modest and is seen only in those at high risk.
A dog living in the home at the time of birth has been associated with a 50% decrease in the incidence of AD at age 3, whereas cat sensitization has been associated with a significantly increased risk.
There does not seem to be an association between vaginal or cesarean birth and development of AD.
Learn more about the etiology of AD.
Medscape © 2021 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Dirk M. Elston. Fast Five Quiz: Pediatric Atopic Dermatitis - Medscape - Jun 07, 2021.
Comments