Fast Five Quiz: Pediatric Atopic Dermatitis

Dirk M. Elston, MD


June 07, 2021

Increased levels of IL-4 and IL-13 are seen in acute AD skin lesions, whereas chronic AD lesions show increased expression of IL-5 and IL-12 and IFN-γ.

Although AD is often associated with elevated serum IgE levels and the total IgE level in some cases correlates with disease severity, the measure is not a reliable indicator. Some patients with severe disease show normal values, and IgE may also be elevated in multiple nonatopic conditions, such as cancers and autoimmune diseases.

Learn more about the pathophysiology of AD.


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