Acute lymphoblastic leukemia (ALL) represents the malignant alteration and proliferation of lymphoid progenitor cells, or lymphoblasts, in the bone marrow, blood, and extramedullary sites. It is the second most common acute leukemia in adults. From 1990 to 2017, the number of ALL cases worldwide increased from 49,100 to 64,200. Patients with ALL may experience anemia, thrombocytopenia, and neutropenia, although usually not to the extent that is seen in acute myeloid leukemia (AML). Lymphoblasts can also penetrate sites outside the bone marrow, such as the lymph nodes, liver, and spleen, resulting in organ enlargement.
In recent years, expanding knowledge of the biology of ALL has improved the management and outcomes of patients with ALL.
How much do you know about ALL? Test your knowledge with this quick quiz.
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Cite this: Karen Seiter. Fast Five Quiz: Acute Lymphoblastic Leukemia (ALL) - Medscape - Aug 18, 2021.