Fast Five Quiz: Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Neera K. Dahl, MD, PhD

Disclosures

August 06, 2021

Autosomal-dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease and the fourth leading cause of end-stage renal disease worldwide. As many as 12 million people are affected by ADPKD, which stems primarily from mutations of the PKD1 and PKD2 genes, and less often from mutations of the GANAB and DNAJB11 genes. Cyst formation and enlargement of the kidney and other organs (eg, liver, pancreas, spleen) are its hallmark characteristics. Recently, there have been numerous advances in understanding of the molecular genetics and biology of ADPKD, and in the diagnosis and management of its manifestations. Yet, in the absence of broadly accepted practice guidelines, its diagnosis, evaluation, prevention, and treatment remain challenging and variable.

How much do you know about ADPKD? Test your knowledge with this quick quiz.

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