Fast Five Quiz: Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Neera K. Dahl, MD, PhD


August 06, 2021

Figure 1. Polycystic kidney disease.

Approximately 7 in 10 patients with ADPKD progress to kidney failure. Patients typically begin dialysis in the latter half of the fifth decade of life, with a median age of 58 years; however, patients may develop kidney failure earlier in life.

Men tend to have more severe ADPKD than women and have higher rates of progression to kidney failure. However, an observational study found that women are twice as likely as men to be diagnosed with ADPKD in young adulthood, possibly due to abdominal ultrasound examinations during pregnancy. Men are more often diagnosed after the progression of kidney disease.

Learn more about the epidemiology of ADPKD.


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