For mild to moderate pain, weak opioids such as tramadol, dihydrocodeine, and codeine can be given together with nonopioid analgesics. For moderate nononcologic pain, opioid-naive patients should receive nonopioid and adjuvant therapies in combination with titration of short-acting opioids as needed.
As an alternative to weak opioids, low doses of strong opioids could be an option, but this recommendation is not currently part of WHO guidance. Of note, there is no evidence of increase in adverse effects from the use of low-dose strong opioids instead of the standard step 2 approach with weak opioids.
Learn more about palliative management of cancer pain.
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Cite this: Winston W. Tan. Fast Five Quiz: Oncology Pain Management - Medscape - Jul 19, 2021.