If more than four rescue doses per day become necessary, the baseline opioid treatment with a slow-release formulation should be adapted.
All patients should receive a provision of a "rescue" or breakthrough dose to manage exacerbations of pain, usually 10%-20% of the total daily dose. Opioids with a rapid onset of analgesia and short duration are recommended for these episodes. Individual titration, or administering normal-release morphine every 4 hours with the addition of rescue doses (up to hourly), is also recommended for breakthrough pain.
Learn more about palliative management of cancer pain.
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Cite this: Winston W. Tan. Fast Five Quiz: Oncology Pain Management - Medscape - Jul 19, 2021.