Fast Five Quiz: KRAS Mutations in Non-Small Cell Lung Cancer

Winston W. Tan, MD; Maurie Markman, MD


August 16, 2022

Figure 1. Adenocarcinoma of the lung.

Molecular profiling of lung adenocarcinomas has shown that specific demographic and clinicopathologic characteristics are associated with the presence of KRAS mutations. KRAS mutations occur much less often in patients of Asian descent, per Izumi and colleagues. According to a pooled analysis of patients with resected NSCLC tumors, KRAS mutations also tend to be more common among women and younger patients, although sex was not shown to be a significant factor during multivariate analysis.

Learn more about the epidemiology of KRAS-mutated NSCLC.


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