Lixisenatide is a once-daily injectable GLP-1 receptor agonist used in patients with type 2 diabetes. GLP-1 agonists delay gastric emptying, which may affect the absorption of concomitantly administered medications. Lixisenatide can decrease the level and effect of acetaminophen; modification to therapy or close monitoring is recommended. Serious interactions with acetaminophen may occur in patients taking lonafarnib, pexidartinib, or pretomanid.
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Cite this: Mary L. Windle. Fast Five Quiz: Acetaminophen - Medscape - Jul 22, 2021.