Heart failure is a significant clinical and public health concern that affects approximately 26 million people worldwide. Nearly 50% of heart failure cases are heart failure with reduced ejection fraction (HFrEF). HFrEF, also referred to as systolic heart failure, arises when the left ventricular ejection fraction is ≤ 40% and is accompanied by progressive left ventricular dilatation and adverse cardiac remodeling. After hospitalization for HFrEF, the 5-year mortality rate is as high as 75%, particularly among older adults. Treatment aims to address underlying and associated conditions to reduce morbidity and mortality and improve clinical outcomes.
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Cite this: Alanna Morris, Michael Weber, Jeffrey J. Hsu. Fast Five Quiz: Heart Failure With Reduced Ejection Fraction (HFrEF) Treatment Optimization - Medscape - Mar 13, 2023.