Fast Five Quiz: Heart Failure With Reduced Ejection Fraction (HFrEF) Treatment Optimization

Alanna Morris, MD


September 09, 2021

Figure 1. Heart failure. X-rays of a patient before (left) and after (right) treatment for heart failure. The heart (white) is greatly enlarged at left, obscuring much of the lung (black) on the right of the X-ray plate.

According to the ACC guidelines, either an ARNI/ACEI/ARB or beta-blocker should be initiated in patients with new-onset stage C HFrEF. In many cases, an ARNI/ACEI/ARB and a beta-blocker can be started at the same time, and experts increasingly feel that this approach is most beneficial. Regardless of the initiation sequence, agents should be uptitrated to the highest tolerated dose or to target doses in a timely manner (eg, every 2 weeks).

Learn more about the treatment of HFrEF.


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