Fast Five Quiz: Sildenafil (Viagra)

Mary L. Windle, PharmD


August 04, 2021

In patients with penis deformation (eg, Peyronie disease), sildenafil should be used with caution. Its use should also be closely monitored in patients with conditions that predispose them to priapism, including multiple myeloma and sickle cell anemia.

Sildenafil should also be not administered or used with caution in patients with a history of various cardiovascular conditions, including the following:

  • Angina

  • Arrhythmia

  • Coronary artery disease

  • Heart failure

  • Hyperlipidemia

  • Hypotension or hypertension

  • Myocardial infarction

  • Stroke

Other conditions of concern in patients considering sildenafil include the following:

  • Bleeding disorders

  • Diabetes

  • Eye disorders (eg, retinitis pigmentosa, nonarteritic anterior ischemic optic neuropathy)

  • Kidney disease

  • Leukemia

  • Liver disease

  • Pulmonary veno-occlusive disease

  • Stomach ulcer

Review more on conditions associated with priapism.


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