Fast Five Quiz: Refractory Myasthenia Gravis

Raghav Govindarajan, MD


October 13, 2021

In terms of absolute numbers, anti-AChR is the most common subtype of MG overall. However, a greater proportion of patients with refractory MG are anti-MuSK-positive compared with those who are anti-AChR-positive.

There is indeed heterogeneity in disease course and treatment response based on patient antibody profile. Patients with anti–MuSK-positive antibodies appear to be less responsive to conventional treatment than both patients with anti–AChR-positive antibodies and patients without detectable antibodies.

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