Myasthenia gravis (MG) is the archetype of B-cell–mediated autoimmune disorders. The pathology of MG sets it apart from the bulk of autoimmune diseases because it is caused by autoantibodies with clear pathogenic effects. Symptoms range from a purely ocular form to weakness of the limb, bulbar and respiratory muscles, which are attributed to the unique pathophysiology of impaired neuromuscular transmission, which produces a dynamic disorder governed by the cycle of neuromuscular junction (NMJ) repair.
How much do you know about the physiologic mechanisms underlying MG? Test your knowledge with this quick quiz.
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Cite this: Raghav Govindarajan, Nicholas J. Silvestri. Fast Five Quiz: Pathophysiology of Myasthenia Gravis - Medscape - Sep 15, 2023.