Fast Five Quiz: Pathophysiology of Myasthenia Gravis

Raghav Govindarajan, MD; Nicholas J. Silvestri, MD


September 15, 2023

Myasthenia gravis (MG) is the archetype of B-cell–mediated autoimmune disorders. The pathology of MG sets it apart from the bulk of autoimmune diseases because it is caused by autoantibodies with clear pathogenic effects. Symptoms range from a purely ocular form to weakness of the limb, bulbar and respiratory muscles, which are attributed to the unique pathophysiology of impaired neuromuscular transmission, which produces a dynamic disorder governed by the cycle of neuromuscular junction (NMJ) repair.

How much do you know about the physiologic mechanisms underlying MG? Test your knowledge with this quick quiz.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.