Skill Checkup: A 27-Year-Old Woman With Erythematous Plaques on Her Elbow, Thighs, and Scalp

William James, MD


December 20, 2021

Outpatient topical therapy is the first-line treatment of plaque psoriasis. Topical agents include corticosteroids, calcineurin inhibitors, vitamin D analogs such as calcipotriene, tazarotene, salicylic acid, anthralin, and coal tar. Often, a rotational therapeutic approach is used to minimize the adverse-effect profiles of a single agent. Topicals are frequently used as adjunctive therapies for patients on phototherapy, systemic, or biologic therapy.

No single topical agent is uniformly effective for plaque psoriasis, and, as stated, many are often used concurrently in a combined approach.


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