Fast Five Quiz: Immunosuppression for Kidney Transplantation

Ron Shapiro, MD


October 22, 2021

Delayed wound healing is a known side effect of mTOR inhibitors. Other side effects include leukopenia, thrombocytopenia, increased risk of infections, hyperlipidemia, and life-threatening pneumonitis.

Anti-CD25 antibodies can enhance the risk of developing the following toxicities: hypersensitivity reactions, infectious complications, malignancies, and myelosuppression.

Antiproliferative agents can lead to leukopenia, thrombocytopenia, neutropenia, hepatotoxicity, anorexia, increased incidence of tumors, and opportunistic infections.

Because antithymocyte globulins are xenogenic proteins, their use is associated with fever and chills. They can also cause cytokine-release syndrome, lymphopenia, and increased risk of post-transplant lymphoma.

Learn more about the toxicity profiles of immunosuppressants.


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