Fast Five Quiz: COVID-19 Vaccines

Glenn Wortmann, MD


October 15, 2021

Figure 1. Conceptual image of the COVID-19 vaccine.

An mRNA vaccine (BNT162b2, Pfizer/BioNTech) is currently the only COVID-19 vaccine that has received full FDA approval for use in the United States. This vaccine can be marketed for the prevention of COVID-19 in individuals aged 16 years and older. It is also available in the United States under emergency use authorization in other scenarios, including to provide a two-dose primary series for individuals aged 12 years and older, a third primary series dose for individuals aged 12 years and older who have certain immunocompromising conditions, and a single booster dose for:

Another mRNA vaccine (mRNA-1273, ModernaTX, Inc.) is also authorized for emergency use in the United States in two doses separated by 28 days in individuals aged 18 years and older, and as a single booster dose in the same age group for individuals who have undergone solid organ transplantation or who are immunocompromised. A third COVID-19 vaccine (JNJ-78436735, Janssen Pharmaceuticals Companies of Johnson & Johnson), which is a viral vector vaccine, is authorized for emergency use in the United States as a single shot in individuals aged 18 years and older.

Many COVID-19 vaccines using other platforms, such as DNA, protein subunit, inactivated virus, and live attenuated virus, are also in development, and several of these have been authorized or approved for use in countries around the world.

Learn more about COVID-19 vaccines.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.