Fast Five Quiz: Sézary Syndrome

Lauren C. Pinter-Brown, MD


November 01, 2021

Molecular studies, including detection of a clonal T-cell receptor gene rearrangement by PCR and the presence of a clonal cytogenetic abnormality, provide evidence of T-cell clonality. An alternative approach to demonstrate T-cell clonality incorporates multicolor flow cytometry, using a panel of antibodies specific for various T-cell receptor beta-chain variable region family members.

Learn more about diagnosis of Sézary syndrome.


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