The Follicular Lymphoma International Prognostic Index (FLIPI) considers five independent predictors of poorer survival: age > 60 years, hemoglobin < 12 g/dL, higher than normal serum LDH, Ann Arbor stage III/IV, and more than four involved nodal areas. The presence of zero or one, two, or three or more adverse factors categorizes a patient as having low, intermediate, or high-risk disease, respectively. Established prognostic indices do not incorporate duration of response to initial therapy.
Other indices include FLIPI2 and GELF (Groupe d'Etude des Lymphomes Folliculaires).
Learn more about prognostic factors in FL.
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Cite this: Emmanuel C. Besa. Fast Five Quiz: Progression of Follicular Lymphoma - Medscape - Nov 10, 2021.